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The principal cytochrome P450 isoenzyme concerned appears to get CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Approximately eighty five% of an oral dose appears within the urine within just 24 several hours of administration, most as the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for to